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serotype 3 spn  (ATCC)


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    ATCC serotype 3 spn
    A) Schematic of experimental model used. B) Spn <t>serotype</t> <t>3</t> CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.
    Serotype 3 Spn, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 54 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spn+serotype+3/Sp3/bio_rxiv__64898__2026__01__05__697792-117-15-19
    Average 94 stars, based on 54 article reviews
    serotype 3 spn - by Bioz Stars, 2026-09
    94/100 stars

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    1) Product Images from "Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation"

    Article Title: Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation

    Journal: bioRxiv

    doi: 10.64898/2026.01.05.697792

    A) Schematic of experimental model used. B) Spn serotype 3 CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.
    Figure Legend Snippet: A) Schematic of experimental model used. B) Spn serotype 3 CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.

    Techniques Used: Infection

    Related Articles

    Infection:

    Article Title: Critical role of IL22/IL22RA1 signaling in pneumococcal pneumonia
    Article Snippet: .. Experimental Spn mouse infection One fresh colony of Spn serotype 3 (ATCC 6303) was grown in 100 ml of Todd-Hewitt broth for 10 hours at 37°C, 5%CO 2 . ..



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    A) Schematic of experimental model used. B) Spn <t>serotype</t> <t>3</t> CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.
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    A) Schematic of experimental model used. B) Spn <t>serotype</t> <t>3</t> CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.
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    A) Schematic of experimental model used. B) Spn <t>serotype</t> <t>3</t> CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.
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    A) Schematic of experimental model used. B) Spn serotype 3 CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.

    Journal: bioRxiv

    Article Title: Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation

    doi: 10.64898/2026.01.05.697792

    Figure Lengend Snippet: A) Schematic of experimental model used. B) Spn serotype 3 CFU counts 24 hours post infection (hpi). Dotted line indicates the bacterial load in the challenge inoculum. Ordinary one-way ANOVA. C) Neutrophil numbers in BAL of naive and Spn experienced WT and IFN-γ KO mice 8 hpi. Lognormal ordinary one-way ANOVA. D) Graphical abstract illustrating our proposed working model of second-order cross-regulation between type 1 and type 3 inflammatory cytokines within non-lymphoid tissues. p value: ns≤ 0.1234, *≤ 0.0332, **≤ 0.0021, ***≤ 0.0002, ****≤ 0.0001. All data have n≥3 mice, 2 experiments, mean ± SEM.

    Article Snippet: On day 36, the mice were intratracheally challenged with 1 × 10 6 CFU of serotype 3 Spn (Sp3, ATCC 6303), suspended in 100μL of sterile PBS.

    Techniques: Infection